However, the roles ubiquitous factors play in the specification of cellidentity remain underappreciated.
3
In combination with molecular instructions, the physical principles behind cellidentity determination are examined.
4
Therefore, stabilizing β- cellidentity upon isolation may improve its functionality.
5
Gene regulation by transcription factors (TFs) determines developmental programs and cellidentity.
1
The ID2 protein supports cancer hallmarks including the cancer stem cellstate.
2
Therefore, it allows for a continuous investigation of the cellstate during stretching experiments.
3
Populations of isogenic cells often respond coherently to signals, despite differences in protein abundance and cellstate.
4
Our understanding of the cellular and molecular mechanisms underlying the adult neural stem cellstate remains fragmentary.
5
These findings demonstrate that somatic cellstate influences requirements for reprogramming and delineate two phases in the process.
1
All fish generate electricity with a specialized typeofcell called an electrocyte.
2
Embryonic stem cells, or ESCs, can grow into any other typeofcell.
3
A variety of stimuli can induce this typeofcell death.
4
Significance: Mitochondria are structurally and biochemically diverse, even within a single typeofcell.
5
This typeofcell, however, has many serious disadvantages inherent to its very nature.
1
Previous studies highlight CARM1's importance in the differentiation of different celltypes.
2
Mitoflashes are fundamental events present in a wide range of celltypes.
3
However, its solubility in Triton is different in the two celltypes.
4
This mechanism might be common to other celltypes, including tumor cells.
5
Furthermore, for certain applications the targeting of specific celltypes is desirable.
1
Objective: The mast cellsubtype of two patients with mastocytosis was investigated.
2
T-helper cellsubtype specific cytokines and transcription factors were quantified using real-time polymerase chain reaction.
3
These changes are cellsubtype-specific and affect the ability of SSTR agonists to inhibit cell proliferation.
4
Histologic grade, presence of necrosis, and sarcomatoid differentiation provided independent prognostic information on the clear cellsubtype of renal cancer.
5
Malignant lymphomas of the diffuse mixed or diffuse large cellsubtype are immunologically heterogeneous and morphologic features do not allow prediction of lineage.
1
Age-adjusted incidence rates of all evaluated B- cellsubtypes were significantly higher in U.S.
2
Mast cellsubtypes were measured with a double sequential immunostaining method.
3
Survival analysis of pancreatic cancer patients was stratified by tumour infiltrating immune cellsubtypes.
4
DNA was isolated from the desired cellsubtypes and enzymatically hydrolyzed to the free deoxyribonucleosides.
5
Th cellsubtypes and Treg numbers were counted with the aid of multi-color flow cytometry.
1
Previous studies highlight CARM1's importance in the differentiation of different celltypes.
2
These associations were celltype specific and reflected the cell's physiological state.
3
Recent evidence suggests that stochasticism is important for generating celltype diversity.
4
Mitoflashes are fundamental events present in a wide range of celltypes.
5
However, its solubility in Triton is different in the two celltypes.
1
Previous studies highlight CARM1's importance in the differentiation of different celltypes.
2
These associations were celltype specific and reflected the cell's physiological state.
3
Recent evidence suggests that stochasticism is important for generating celltype diversity.
4
Mitoflashes are fundamental events present in a wide range of celltypes.
5
However, its solubility in Triton is different in the two celltypes.
Ús de cell subset en anglès
1
These culture conditions did not select for a particular T cellsubset.
2
The recruitment of this cellsubset may be driven by CCL20 chemokine.
3
In humans, a dedicated NK cellsubset primarily fulfills these later functions.
4
Furthermore, this cellsubset is characterized by poor expression of surface Ig's.
5
Together, these results suggest a distinct function for each diabetogenic T cellsubset.
6
The CD3-stimulated IFN-gamma production from each T cellsubset was augmented by macrophages.
7
This T- cellsubset was previously shown to be necessary for development of the disease.
8
These findings define two distal regulatory elements associated with T cellsubset-specific IFN-gamma expression.
9
Yet, whether this NK cellsubset is directly involved in the therapeutic effect is unknown.
10
To better characterize the spindle cellsubset of metaplastic breast carcinomas, we reviewed 29 cases.
11
We identified an unusual polyclonal expansion of the IgM memory B cellsubset in some patients.
12
Dependent on the molecule disrupted, the immune cellsubset being examined may no longer be appropriately regulated.
13
During HCV-infection, this T cellsubset may release Th1 cytokines and contribute to the necroinflammatory liver disease.
14
A fraction of these cells self-renew and persist as a minor B1 B cellsubset throughout life.
15
Recently, the newly described stem memory T cellsubset has also been implicated as a long-lived HIV reservoir.
16
This B cellsubset is known to be tightly regulated, and autoreactive cells are eliminated by tolerance mechanisms.